What You Should Know
- Harvard Medical School’s Center for Primary Care has released a comprehensive "Primary Care Investment Guide," providing the first evidence-based roadmap for deploying capital into team-based care models.
- The report identifies six critical "Advanced Primary Care" (APC) services—including behavioral health integration and e-consults—that demonstrate measurable ROI through reduced hospitalizations and improved equity.
- With the U.S. spending only 4.6% of
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The 2025 Margin Rally: Hospitals See Late-Year Gains Despite Soaring Drug Costs
What You Should Know:
- U.S. health systems recorded their strongest financial improvement of the year in November 2025, with median year-to-date operating margins rising to 1.5%, marking the fourth consecutive month of gains.
- Despite this stability, hospitals remain under significant pressure from rising expenses, particularly a 9.3% year-over-year spike in drug costs and increasing financial strain on physician practices. While revenue is growing, high operational costs suggest that
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Cornell Survey: Experts Warn HSA Conversion and Small Premiums Threaten ACA Affordability
What You Should Know:
- A new survey from the Cornell Health Policy Center reveals that 70% of health policy scholars believe converting ACA subsidies into Health Savings Accounts (HSAs) would worsen affordability for enrollees.
- Additionally, 81% of experts agree that ending automatic renewals—a policy slated for 2028 under the "One Big Beautiful Bill Act"—will substantially reduce Marketplace enrollment. These findings come as policymakers scramble to find alternatives to enhanced
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The “One Shot” Cure? How Vyriad’s $85M Raise Could Replace Complex CAR-T Labs with a Single Injection
What You Should Know:
- Vyriad, Inc. has secured the final $25M of its Series B financing, bringing the total round to $85M led by Mr. Harry Stine of Stine Seed Farms, Inc.
- The funding will power the first-in-human trials of VV169, an in vivo CAR-T therapy for multiple myeloma that modifies immune cells directly inside the patient’s body. This approach eliminates the complex, expensive lab manufacturing required by current CAR-T treatments, potentially offering a scalable,
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HCAP Partners Invests in Puzzle Healthcare to Scale Post-Acute Care Platform
What You Should Know:
- Private equity firm HCAP Partners has invested in Puzzle Healthcare to scale a post-acute care platform designed to stop the "revolving door" between hospitals and skilled nursing facilities (SNFs).
- Puzzle’s model embeds specialized physiatry providers and care managers into SNFs to coordinate recovery for 90 days post-discharge, directly tackling the high readmission rates that cost hospitals millions in CMS penalties. The funding will support national
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Catalyst by Wellstar Launches Polysight: An AI-Native Compliance Platform for Health Systems
What You Should Know
- Catalyst by Wellstar has launched Polysight, a new AI-native company designed to tackle the $39 billion annual cost of U.S. healthcare compliance.
- The platform uses validated regulatory sources and real-time data to automate what has historically been a fragmented, manual process. Currently piloting with Wellstar Health System, Polysight aims to modernize how hospitals anticipate and adapt to changing regulations without sacrificing patient safety.
$39 Billion
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WakeMed Partners with Rezilient Health to Launch Hybrid CloudClinics for Employees in 2026
What You Should Know:
- WakeMed Health & Hospitals has partnered with hybrid healthcare startup Rezilient Health to launch four "CloudClinics" in the Raleigh-Durham area starting January 2026.
- The new model allows employees to access same-day primary and specialty care via a unique blend of remote physicians beamed into clinics staffed by on-site medics and diagnostic tools.
- Initially available to WakeMed’s 12,000 employees, the service aims to reduce healthcare
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Healthcare 2026 Forecast: Executives on AI Survival, Financial Reckoning, and the End of Point Solutions
As we peer into the healthcare horizon of 2026, a singular theme crystallizes among industry leaders: the transition from aspirational innovation to operational necessity. The executive predictions for the coming year depict a sector at a critical inflection point, where financial survival dictates that technology must evolve from fragmented point solutions into orchestrated, interoperable ecosystems.
The narrative has shifted from the mere adoption of AI to a rigorous demand for "glass-box"
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The “Second Opinion” Era: Why 86% of Clinicians Now Trust AI to Catch Missed Details
What You Should Know:
- New flagship research from athenahealth’s intelligence hub reveals a critical maturity milestone in healthcare AI: the shift from experimental admin tools to trusted clinical partners.
- A national survey of 501 clinicians and administrators found that 86% now feel comfortable delegating or sharing the responsibility of catching easy-to-miss details in patient records with AI.
- While adoption is surging—with 62% of practices now using four or more AI
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AVIA Expands Agentic AI Collaborative with Second Health System Cohort and New Catalyst Program
What You Should Know:
- AVIA has expanded its Agentic AI portfolio by launching a second national cohort of seven health systems, including Rush University System for Health and LifeBridge Health, to operationalize AI that "does" rather than just "chats".
- The announcement also introduces "AVIA Nexus Catalyst," a new 12-week program launching in early 2026 powered by Lumeris, specifically designed to co-create AI automation frameworks for primary care. The initiative splits
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