
What You Should Know
– Axena Health has announced a major expansion of its collaboration with Mayo Clinic to develop a new, AI-integrated solution for women with pelvic floor disorders.
– Building on their initial 2025 partnership, the new initiative aims to leverage Mayo Clinic’s clinical expertise to create personalized care pathways that improve treatment adherence for conditions like urinary incontinence and overactive bladder (OAB).
Solving the Adherence Gap: AI as a Clinical Bridge
A critical challenge in women’s pelvic healthcare is the high rate of “care pathway dropout,” where patients stop treatment before achieving clinical results. Axena Health’s new product—separate from its flagship Leva® Pelvic Health System—is designed specifically to address this friction.
- AI-Driven Personalization: The platform will integrate advanced artificial intelligence to analyze patient data, allowing clinicians to deliver more tailored interventions based on individual symptom profiles and adherence patterns.
- Engagement throughout the Journey: The goal is to keep patients actively engaged while enabling providers to seamlessly transition them to second- and third-line treatments when appropriate.
- Framework for Expansion: While the initial focus is on urinary incontinence and OAB, the AI platform is designed to serve as a framework for a wide range of future pelvic health treatment pathways.
The “Systemic” Shift: Meeting Women Where They Are
The collaboration is fueled by a recognized need to modernize a system that often treats women’s biological needs as episodic.
“As a urogynecologist, I see how women with pelvic floor disorders fall off the care pathway before completing treatment—not because they don’t want help, but because the system isn’t built to meet them where they are,” said Dr. Samantha Pulliam, MD, FACOG, Chief Medical Officer and Interim CEO of Axena Health. “This collaboration with Mayo Clinic allows us to work toward tackling that gap head-on by combining Mayo Clinic’s clinical expertise with AI-driven personalization to help clinicians keep patients engaged and deliver more personalized, effective care throughout their treatment journey.”
Rise of ‘Adaptive’ Care Pathways
The expansion of this partnership underscores a broader 2026 trend toward “Agentic Intelligence”—systems that don’t just track data, but actively navigate the user through a clinical process. As Axena and Mayo Clinic build out this framework, we expect it to become a de facto model for how to combine medical institutional knowledge with high-tech personalization to serve underserved patient populations.
