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Clinician-Led Innovation at Scale: Sheba’s ARC Partners with Edge to Launch New Venture Studio

by Fred Pennic 12/10/2025 Leave a Comment

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Edge Medical Ventures Team

What You Should Know: 

– ARC, the innovation arm of Sheba Medical Center, has partnered with Edge Medical Ventures to launch a hybrid venture studio focused on scaling medical device and bio-convergence startups. 

– Backed by over $10M in support from the Israel Innovation Authority, the collaboration aims to fast-track clinician-led technologies by combining Sheba’s clinical environment with Edge’s operational expertise. The initiative builds on an eight-year history of collaboration, aiming to bridge the gap between unmet clinical needs and market-ready commercial solutions.

A Hybrid Model: Organic Meets Open Innovation

The core differentiator of this partnership is its dual-track approach to sourcing innovation.

  1. Organic Innovation: This track focuses on the internal intellectual property. Ideas emerging directly from ARC’s clinical environment—from surgeons, nurses, and researchers—will be processed through Edge’s venture studio expertise.
  2. Open Innovation: This track looks outward. Leveraging Edge’s deal flow, the partnership will fast-track promising external concepts by validating them against ARC’s massive clinical assets and patient data.

“We are excited to take our partnership to the next level, maximizing global, life-saving patient impact by combining our joint strengths,” said Avner Halperin, CEO of Sheba Impact at ARC. “This partnership advances our mission to build clinician-led innovation that delivers both clinical impact and economic value.”

Backed by Government Capital and Historical Success

This alliance is not starting from zero. It builds on eight years of collaboration between Sheba and the Edge team, previously operating through the MEDX Xelerator. That relationship has already produced notable exits and successes, including Append Medical and Synchrony Medical, companies that successfully navigated the path from concept to clinical utility.

Validation for this new chapter comes in the form of significant non-dilutive funding. Edge was recently selected by the Israel Innovation Authority as the sole healthcare deep-tech fund in its new incubator program. This designation comes with over $10M in support, capital that will be used to de-risk early-stage technologies before they face the harsh realities of the global market.

The Rise of the Physician-Entrepreneur

A key component of the ARC-Edge strategy is the cultivation of human capital. The initiative goes beyond product development to focus on training. The partnership includes specialized programs, such as cardiology innovation courses, designed to transform practicing clinicians into physician-entrepreneurs.

By embedding engineers and scientists alongside clinicians, the initiative aims to solve “unmet clinical needs”—a phrase often overused in the industry, but here backed by the daily realities of Sheba Medical Center’s patient load.

“By combining proven clinical validation with the venture studio model, we aim to create companies that address the most pressing challenges in healthcare,” said Shai Policker, CEO of Edge Medical Ventures.

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