What You Should Know:
– Ambience Healthcare, an ambient AI platform for documentation, coding, and clinical documentation integrity (CDI), today announced a $243M Series C funding round.
– Co-led by Oak HC/FT and Andreessen Horowitz (a16z), the round saw participation from existing investors including the OpenAI Startup Fund, Kleiner Perkins, and Optum Ventures.
– New investors include Frist Cressey Ventures, Town Hall Ventures, Smash Capital, Georgian, and Founders Circle Capital. This significant investment will enable Ambience to scale its AI platform across health systems nationwide.
Transforming Clinical Workflows Across the Continuum of Care
– Ambience Healthcare was designed with the understanding that health systems are complex enterprises, spanning ambulatory clinics, emergency departments, and inpatient hospitals, each with distinct workflows, specialties, and demands. The platform integrates directly into the EHR, adapting to the unique context of each care setting and specialty without requiring workflow redesign or staff retraining.
The Ambience AI platform delivers tailored benefits to all key stakeholders in the healthcare ecosystem:
- For Clinicians: Automates documentation with ambient listening, preps them with specialty-specific chart summaries, and simplifies complexity with built-in features like ICD-10 assistant and a real-time compliance engine—all directly inside their existing EHR workflow. This reduces cognitive burden and documentation time, freeing clinicians to focus on delivering their best patient care.
- For Administrators: Standardizes workflows across coding, quality, CDI, prior authorization, and utilization management by producing complete, compliant documentation in real time. It includes built-in support for CDI & ICD-10 coding assist and structured chart output tailored for operational review—all at leading levels of compliance from data captured throughout the entire clinical workflow.
- For Patients: Enhances understanding and care follow-through with contextually aware ambient listening and clear after-visit summaries. With Ambience handling documentation in the background, clinicians remain more engaged, strengthening trust, communication, and overall care experience.
Transforming Clinical Workflows Across the Continuum of Care
Building on its foundation of industry-leading ambient scribing, Ambience has evolved into a comprehensive end-to-end platform for documentation, coding, and clinical workflow support that operates across the full continuum of care. Today, it supports more than 100 ambulatory subspecialties, emergency departments, and inpatient specialties, producing structured, compliant documentation that:
- Improves clinical quality.
- Reduces administrative burden.
- Drives revenue-cycle performance.
The platform is powered by proprietary AI reasoning models purpose-built to handle the nuanced regulatory, clinical, and operational demands of real-world healthcare.
Improved Coding Accuracy & Compliance
Ambience is currently used by leading health systems across the United States, including Cleveland Clinic, UCSF Health, Houston Methodist, and Memorial Hermann. Adoption has been fastest in high-complexity subspecialties, emergency departments, and inpatient settings—areas with the greatest documentation burden. In recent KLAS evaluations, Ambience achieved a 97.7 customer satisfaction score, earning top marks for product quality and responsiveness. It is also the first ambient solution with third-party validated, CFO-approved ROI tied to improved coding accuracy and compliance.
Michael Ng, CEO of Ambience Healthcare, stated, “Documentation has long been a source of friction. Ambience is turning it into a source of strength – transforming how clinicians deliver care, how administrators run operations, and how patients experience the system.”
Ambience Healthcare will continue expanding its AI platform across health systems and accelerate the delivery of products that make administrative tasks invisible, data accurate by default, and care teams more effective everywhere.
