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Wolters Kluwer Health Launches UpToDate® Expert AI to Accelerate Clinical Decisions

by Syed Hamza Sohail 09/24/2025 Leave a Comment

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What You Should Know:

– Wolters Kluwer Health today announced UpToDate® Expert AI, a new generative AI-powered clinical decision support (CDS) solution designed to support the needs of both doctors and healthcare systems.

– UpToDate Expert AI sets a new standard in how healthcare professionals can easily access evidence-based answers to medical questions at the point of care, while supporting healthcare organizations’ efforts to responsibly integrate AI into their infrastructure and workflows.

Global Leader in Professional Information and Solutions

Wolters Kluwer (EURONEXT: WKL) is a global leader in expert information, software solutions, and services across healthcare, tax and accounting, financial and corporate compliance, legal and regulatory, corporate performance, and ESG. The company equips professionals with the knowledge and tools needed to make critical decisions every day by combining deep domain expertise with advanced technology.

In 2024, Wolters Kluwer reported annual revenues of €5.9 billion. The organization serves customers in more than 180 countries, operates in over 40 markets, and employs around 21,600 people worldwide. Its global headquarters is located in Alphen aan den Rijn, the Netherlands.

Introducing UpToDate Expert AI: GenAI-Powered Clinical Intelligence

UpToDate Expert AI represents the next evolution of UpToDate, the market-leading clinical decision support (CDS) solution trusted by thousands of hospitals worldwide. Designed to function like a conversational assistant, it delivers rapid, GenAI-powered answers to clinical questions based on UpToDate’s rigorously peer-reviewed and expert-authored content.

Clinicians receive context-rich responses with:

  • Transparent access to the assumptions and sources behind each recommendation
  • Step-by-step rationale showing how conclusions were derived
  • Direct links back to UpToDate content for further review

“With UpToDate Expert AI, we are responding to our customers’ needs to apply the speed and power of GenAI for reliable, trustworthy medical answers while adding value into the enterprise workflow,” said Greg Samios, CEO of Wolters Kluwer Health.

UpToDate Expert AI is powered by Clinical Intelligence, a unique reasoning approach that emulates how expert clinicians think and act. Its multi-layered validation framework is guided by Wolters Kluwer’s global network of 7,600 medical experts. This ensures that algorithms remain expert-driven throughout the interaction, rapidly synthesizing complex information into actionable insights that support faster, more informed patient care.

The solution is continuously updated as UpToDate editors and authors review emerging evidence from leading medical journals, clinical trials, pharmacology studies, drug labeling, and MEDLINE abstracts.

Purpose-built for enterprise-wide deployment, UpToDate Expert AI integrates seamlessly across technology ecosystems, embedding directly into EHRs, AI scribes, and other core platforms. This deep integration minimizes workflow disruptions, strengthens compliance and governance, and enables clinicians to focus more fully on patient care.

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