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Quilt Health Raises $6M to Modernize Clinical Trial Access for Complex Diseases

by Fred Pennic 06/17/2025 Leave a Comment

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Founders Andy Ellner, MD & Jazmine Coleman, MBA

What You Should Know: 

– Quilt Health, a digital health company dedicated to bridging gaps in treatment access for complex diseases secures $6M in seed funding round, bringing its total funding to $8M. The round was led by MaC Venture Capital and Underscore Ventures, with participation from Meridian Street Capital, BoxGroup, Watershed VC, and Coalition Operators.

– Founded with an initial focus on sickle cell disease, the company plans to use the new capital to rapidly expand into other hematologic, neurological, and cardiovascular disorders, addressing the broader challenges faced by millions of people living with complex conditions.

Closing the Gap Between Care and Research

Quilt Health is modernizing clinical trial access by expanding the number and type of sites included in trials and bridging the gap between real-world care and research. Despite decades of innovation, clinical trials remain plagued by an outdated and inefficient recruitment process. This problem is magnified in rare disease research, where patient pools are small and hard to reach, resulting in more than 70% of trials failing to meet their enrollment thresholds.

Quilt Health’s technology addresses this by supporting clinical workflows through the integration of multiple data sources and applying AI to unstructured data to surface key patient characteristics and outcomes.

The company’s platform is designed to benefit the entire clinical trial ecosystem:

  • For Pharmaceutical Sponsors: Quilt’s network and platform accelerate trial execution, reduce operational costs, and support more representative patient enrollment, which is a critical factor in improving trial diversity.
  • For Research Sites and Clinicians: They gain access to streamlined workflows, enhanced data collection tools, and hands-on recruitment support, allowing them to focus more on delivering high-quality care and research.
  • For Patients: The platform’s engagement tools keep patients and clinicians connected between visits, improving care and making cutting-edge treatments more accessible.

NASCC Partnership

In addition to its funding, Quilt Health recently announced a partnership with the National Alliance of Sickle Cell Centers (NASCC). With more than 115 sickle cell centers represented, NASCC provides Quilt Health with a national network for combining research and patient care.

“Together, we are creating a more effective, national, patient-centered ecosystem that speeds up the path to market for life-saving treatments,” said Andy Ellner, Founder and CEO of Quilt Health.

The new funding will be used to accelerate product development, fuel R&D, and expand the Quilt Health team. The company will also focus on partnering with high-quality health systems in regions of the country that have not traditionally benefited from major life sciences investment.

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Tagged With: Clinical Trials

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