What You Should Know:
– Twin Health, Mountain View, CA-based makers of the Whole Body Digital Twin™ precision health service, today announced $140 million in Series C funding as it scales its service in the U.S. and globally from investors ICONIQ Growth, Sequoia Capital India, Perceptive Advisors, Corner Ventures, LTS Investments, Helena and Sofina.
– Powered by artificial intelligence, the Whole Body Digital Twin™ is a dynamic representation of each individual’s unique metabolism, built from thousands of data points collected daily via non-invasive wearable sensors and self-reported preferences. The Whole Body Digital Twin™ is a predictive model that provides individualized nutrition, sleep, activity and breathing guidance to patients and their healthcare providers, helping to reverse and prevent multiple chronic metabolic diseases.
Whole Body Digital Twin™ Service Enabling Reversal and Prevention of Chronic Metabolic Disease
Chronic metabolic disease is widespread and growing. The global prevalence of Metabolic Syndrome is estimated as 20-25%. Worldwide, 415 million people are living with diabetes, and more than 500 million will have diabetes by 2040, according to the CDC. Chronic metabolic diseases, such as type 2 diabetes, can start as an individual’s metabolism breaks down over time. Medical research has demonstrated that each person’s metabolism functions uniquely, presenting significant challenges to healthcare providers’ understanding and ability to customize treatment for every single person. For the first time, the Whole Body Digital Twin™ addresses this complexity using cutting-edge technology and advanced medical science to deliver personalized, precise and timely insights with recommendations to address the root cause.
Twin Health’s service is an all-inclusive program consisting of multiple sensors including continuous glucose monitors and fitness watches, comprehensive blood tests and the development of each member’s individualized Whole Body Digital Twin™, as well as consultations with healthcare providers and Twin coaches. The Whole Body Digital Twin™ technology continuously monitors the health of the individual and enables healthcare providers and Twin coaches to take quick actions. Through an easy-to-use app, patients and their care team are provided individualized, precise, timely guidance across nutrition, sleep, activity and breathing. Healthcare providers can access organized biomarker data and medication reduction recommendations for their patients, with the goal of reversing chronic disease. The Twin service is available today via partner programs such as employer benefits or health insurance plans.
“We are each gifted a body. If given a chance, it can heal itself. Our Whole Body Digital Twin™ lives alongside you – giving you a view into your beautifully complex biology, continuously learning about your metabolism and telling you what you can do to improve your health in the moment,” said Jahangir Mohammed, Founder and CEO of Twin Health.
Recent Clinical Research Outcomes/Results
Twin Health’s clinical research team is conducting the world’s first randomized controlled trial (RCT) for reversing chronic metabolic disease using digital twin technology. Early RCT data were recently presented
and published in the American Diabetes Association’s Diabetes journal, with first of its kind health outcomes. Patients had an average HbA1c reduction of 3.1 (average baseline 8.7) with over 90% achieving type 2 diabetes reversal (HbA1c less than 6.5), and 92% eliminating all diabetes medications including insulin.
Furthermore, patients had an average weight reduction of 9.1 kg (20 lbs). Among patients with baseline abnormal liver function (as defined by an elevated ALT on clinical lab values) there was an average ALT reduction of 24 units/L. In comparison, the control group did not achieve diabetes reversal, any reduction in diabetes medications, or a significant improvement in weight or liver function. The scientific outcomes from the RCT and the commercial results have been published in 13 peer-reviewed international medical journals and conference papers and abstracts.
“The Whole Body Digital Twin™ is delivering a new standard of care, empowering physicians and patients to make highly personalized data-driven decisions based on real-time feedback coming from patients’ own bodies,” said Dr. Toby Cosgrove, Executive Advisor/Cleveland Clinic, who is on Twin Health’s board of directors.
